The Role of SUDOSCAN® in Intradialytic Hypotension

The Role of SUDOSCAN® in Predicting Intradialytic Hypotension: Electrochemical Skin Conductance as a New ToolIn this study, conducted by P. Reach et al from Groupe Hospitalier Saint-joseph in Paris, France, the clinical utility of SUDOSCAN® in predicting intradialytic hypotension (IDH) in hemodialysis patients was investigated. IDH is a common complication in HD patients associated with cardiac dysfunction and alterations of the peripheral autonomic nervous system. The study aimed to identify patients at risk of IDH to tailor more personalized dialysis therapy.176 hemodialysis patients with an average age of 64 ±14 years were assessed for dysautonomia by measuring hand and foot Electrochemical Skin Conductance (ESC) using SUDOSCAN before hemodialysis. The primary endpoint was the incidence of IDH based on the presence of a pathological hand and/or foot ESC value during the 3-month study period.The results showed that a pathological hand ESC, as assessed by a non-invasive SUDOSCAN test, was associated with an increased risk of IDH. The study concluded that SUDOSCAN can be a useful tool in predicting IDH and tailoring personalized dialysis therapy.Graphical abstract:Key words: dialysis, electrochemical skin conductance, intra-dialytic hypotension, Sudoscan®Abstract available here.