Long-term monitoring using SUDOSCAN®
Longitudinal Efficacy of SUDOSCAN Results Follow-up
The effectiveness of SUDOSCAN® in monitoring sudomotor function has been demonstrated in various clinical studies. A study conducted in Finland utilized SUDOSCAN to investigate the impact of physical activity on metabolic diseases and cardiovascular risk. The study found that patients with the highest level of weekly physical activity, as measured by a pedometer, experienced the most significant improvement in sudomotor function over a one-year period, resulting in the regeneration of small nerve fibers (1).
Evolution of SUDOSCAN® results among individuals enrolled in a physical activity program for 1 year.
Adapted from (1) – Table 3.
Another study conducted on type 2 diabetic subjects, shows that in bariatric surgery patient population heart rate variability, reflecting cardiac autonomic function, and sudomotor autonomic C-fiber function has been restored over time (2).
Change in primary endpoints 4, 12 and 24 weeks after bariatric surgery.
DM: diabetes mellitus, T2DM: Type 2 diabetes mellitus
Extracted from (2) – Figure 3.
These studies demonstrate that SUDOSCAN is a rapid, non-invasive, quantitative, and objective diagnostic device to follow-up autonomic neuropathy over time.
References:
(1) A. Raisanen et al (J. Tuomilehto). Sudomotor Function as a Tool for Cardiorespiratory Fitness Level Evaluation: Comparison with Maximal Exercise Capacity. Int J Environ Res Public Health. 2014 May 30;11(6):5839-48.
(2) C.M. Casellini et al (A. Vinik). Bariatric Surgery Restores Cardiac and Sudomotor Autonomic C-Fiber Dysfunction towards Normal in Obese Subjects with Type 2 Diabetes. PLoS One. 2016 May 3;11(5):e0154211.